best eso disease dps sets
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ESO Disease DPS Sets

Welcome to my Best Disease DPS Sets for ESO Guide! This Guide will show you the Best 5-piece Armor and Monster Sets for Disease DPS in The Elder Scrolls Online. Amazing Sets that can complement your Stamina Necromancer Build or help you create a powerful Disease DPS Build in ESO!

What are the Best Disease DPS Armor Sets in ESO?

These amazing 5-piece Armor Sets, plague your enemies with Disease based Damage and Effects. These are the Best Disease Sets in ESO:

eso best disease dps sets
ESO Best Disease DPS Sets

1. Azureblight Reaper

Azureblight Reaper is a powerful Disease based Set that relies on Damage over Time effects to proc! This makes it a great option for Disease based Builds but also Damage over Time Builds in general. The more DoTs a Build has, the more effective the Set is! You can farm the Set inside the Lair of Maarselok Dungeon in Normal or Veteran difficulty. The Scalebreaker DLC is required to access the Dungeon.

2. Phylactery’s Grasp

Phylactery’s Grasp is another Dungeon Set that deals great Disease damage but also restores Stamina. Its effect triggers when you deal Critical Damage with a Light Attack, so good Light Attack Weaving is necessary to use it effectively. You can farm the Set inside the Graven Deep Dungeon in Normal or Veteran difficulty. The Lost Depths DLC is necessary to enter the Dungeon.

3. Affliction

Affliction deals extra Disease Damage when you deal Damage. It also debuffs enemies with Defile, which makes it a great option for PVP Builds. This is a Heavy Armor Set that you can get from the Vlastarus Vendor in Cyrodiil. For PVE DPS you will have to use it as weapons and jewelry.

4. Swamp Raider

This Set does not deal Disease damage by itself but it boosts instead the damage of your Disease damage abilities. This is why Swamp Raider is an excellent option for Disease based Builds! An Overland Set that you can get in the Shadowfen zone.

5. Legacy of Karth

Legacy of Karth is a Crafted Set that deals Disease Damage but requires the use of Alchemical Poisons. Its effect procs when you deal damage with your alchemical poisons, which makes it a better option for PVP Builds! You can find its crafting stations at the Druadach Redoubt in The Reach zone. You will need the Markarth DLC to access the zone.

6. Plaguebreak

Plaguebreak is an amazing Disease Set that is now however a PVP exclusive! It infects enemies and explodes, dealing massive AOE Disease damage! You can get pieces of this Set from Rewards for the Worthy coffers from PVP activities.

disease dps monster sets eso
Disease DPS Monster Sets(Credit: Zenimax Media Inc.)

What are the Best Disease DPS Monster Sets in ESO?

The Monster Sets below are great if you wish to complement your Disease Build in ESO. They will boost your overall Disease damage and help you clear PVE or PVP Gameplay. The Best Disease DPS Monster Sets are:

1. Velidreth

Velidreth is an amazing DPS Set that deals massive Disease Damage! It summons spores that explode when they contact enemies, dealing massive damage. A great set for every Stamina based DPS Build! The Head drops in Veteran Cradle of Shadows and you can get the Shoulders piece from Urgarlag Chief-Bane. The Shadows of the Hist DLC is necessary to complete the set.

2. Maarselok

Maarselok also deals massive Disease damage but requires the use of melee Heavy Attacks! A strong option that is rather limited. The Head drops in Veteran Lair of Maarselok and you can get its Shoulders from Urgarlag Chief-Bane. The Scalebreaker DLC is necessary to complete the set.

3. Lady Thorn

Lady Thorn deals good Disease Damage but is more a support set for Tank Builds. To trigger its effect you need to first cast a skill that costs Health, then use the synergy it triggers! The Head drops in Veteran Castle Thorn and you can get its Shoulders from Urgarlag Chief-Bane. The Stonethorn DLC is necessary to complete the set.

4. Thurvokun

Thurvokun is another support Set that deals Disease damage. When you take damage it spawns a pool that hurts and debuffs enemies. The Head drops in Veteran Fang Lair and you can get its Shoulders from Urgarlag Chief-Bane. The Dragon Bones DLC is necessary to complete the set.